Ligustrazine monomer against cerebral ischemia/ reperfusion injury

• 作 者: Hai-jun Gao Peng-fei Liu Pei-w
• 机 构: DepartmentofNeurosurgery,DepartmentofNeurosurgery,ClinicalMedicalCollegeofBeihuaUniversity,SchoolofP
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2015年5期
• 关键词: 缺血/再灌注损伤 脑血管病 川芎嗪 单体 保护作用 时间窗口 兴奋性氨基酸 行政管理 nerve regeneration ligustrazine isc
• 基金项目: Funding： This work was supported by a grant from the Health and Family Planning Commission of Heilongjiang Province Research Project in China, No. 2014-195, the Education Department Science and Techno

Ligustrazine(2,3,5,6-tetramethylpyrazine) is a major active ingredient of the Szechwan lovage rhizome and is extensively used in treatment of ischemic cerebrovascular disease.The mechanism of action of ligustrazine use against ischemic cerebrovascular dis