论文部分内容阅读
目的 观察不同正加速度 (+Gz)暴露下人体尿α1 微球蛋白 (α1 M)的变化规律。方法 6名健康男性受试者 ,分别进行抗荷裤配抗荷调压器的抗荷效果试验、抗荷正压呼吸的抗荷效果试验、抗荷裤配抗荷调压器 +PBG +抗荷动作的抗荷效果试验 3组 +Gz暴露。留取每组 +Gz暴露前、+Gz暴露后 30min、+Gz暴露后 2 4h的尿液各 5ml。结果 ①受试者在采用抗荷装备后 ,所达到的 +Gz耐力分别为 6 2 5± 0 5 2G、8 17± 0 2 6G、9 0 0G ;②与 +Gz暴露前相比 ,+Gz暴露后 30min尿α1 M浓度升高 ,差异有显著性意义(P <0 0 5或P<0 0 1) ;③ +Gz暴露后 2 4h与 +Gz暴露后 30min相比 ,尿中α1 M浓度下降 ,差异有显著性意义 (P <0 0 5或P <0 0 1) ,能恢复到基本接近于 +Gz暴露前水平。结论 +Gz暴露所致人体尿中α1 M浓度升高 ,提示加速度可导致肾功能性改变
Objective To observe the changes of urinary α1 microglobulin (α1 M) in human under different positive acceleration (+ Gz) exposure. Methods Six healthy male subjects were tested for anti-stress effect of anti-stress pants with anti-stress regulator, anti-stress effect test of anti-stress breathing, anti-stress pants + anti-stress regulator + PBG + anti Load-bearing effect of anti-Dutch test group 3 + Gz exposure. Pre-exposure + Gz before each group, 30min after + Gz exposure, 24h urine after + Gz 5ml each. Results ① The + Gz endurance of the subjects reached 6 2 5 ± 0 5 2G, 8 17 ± 0 2 6G, 9 0 0G respectively after using the anti-load equipment. ② Compared with the pre-exposure + Gz Urine α1 M concentration increased 30 min after exposure, the difference was significant (P <0 05 or P <0.01); ③ 24 h after + Gz exposure 30 min after + Gz exposure, urinary α 1 M concentration Decreased, the difference was significant (P <0 05 or P <0 01), can be restored to the level close to the pre-exposure + Gz. Conclusions Elevated concentrations of α1 M in the human urine caused by + Gz exposure suggest that acceleration may lead to changes in renal function