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目的:探讨分析甲氨蝶呤联合米非司酮治疗异位妊娠120例患者的临床疗效。方法:选取2014年10月-2015年10月我院妇产科收治的120例异位妊娠的患者,将其随机分为两组,分别是观察组60例和对照组60例。其中对照组给予甲氨蝶呤50mg/m2,每日1次;观察组给予甲氨蝶呤联合米非司酮治疗,米非司酮口服75-150mg/次,每天1次,3天为一个疗程。观察比较两组患者的临床疗效及不良反应发生率。结果:治疗结果显示,观察组的治愈率(90.0%)明显高于对照组(65.0%),差异有统计学意义(P<0.05)。两组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。结论:甲氨蝶呤联合米非司酮治疗异位妊娠的临床疗效显著,不良反应小,值得在临床上广泛推广。
Objective: To investigate the clinical efficacy of methotrexate combined with mifepristone in the treatment of ectopic pregnancy in 120 patients. Methods: A total of 120 patients with ectopic pregnancy admitted to our department from October 2014 to October 2015 were randomly divided into two groups: observation group (60 cases) and control group (60 cases). The control group was given methotrexate 50mg / m2, once a day; the observation group was treated with methotrexate and mifepristone, mifepristone orally 75-150mg / time, once a day for 3 days Course of treatment. The clinical efficacy and the incidence of adverse reactions in the two groups were observed and compared. Results: The results showed that the cure rate of the observation group (90.0%) was significantly higher than that of the control group (65.0%), the difference was statistically significant (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion: Methotrexate combined with mifepristone treatment of ectopic pregnancy significant clinical effects, adverse reactions, it is worth widely clinically.