血流储备分数评估分叉病变单支架术后边支功能的研究

来源 :中国临床实用医学 | 被引量 : 0次 | 上传用户:fxh722744
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目的:探讨血流储备分数(FFR)在指导分叉病变单支架术后边支功能评估中的临床价值。方法选择2013年1月至2014年9月在南京市第一医院行冠状动脉造影示分叉病变的患者168例,将其按随机数字表法分为试验组和对照组,各84例。试验组:主支支架置入后,测边支FFR,FFR<0.80根据情况行球囊扩张或支架置入,FFR≥0.80不处理。对照组:主支支架置入后,QCA测边支直径狭窄百分比(DS%),DS%≥75%根据情况行球囊扩张或支架置入, DS%0.05);(2)造影剂用量:试验组造影剂用量为(58.5±12.8)ml,明显少于对照组的(79.7±9.3)ml,差异有统计学意义(P<0.05);(3)植入支架数量:试验组植入102个,明显少于对照组的145个,差异有统计学意义(P<0.05);(4)MACE发生率:试验组MACE发生率为14.3%(12/84),明显低于对照组的27.4%(23/84),差异有统计学意义(P<0.05)。结论 FFR能准确评估边支血管的功能,有利于选择合适的分叉病变介入策略,减少不必要的支架植入,减少造影剂用量。“,”ObjectiveTo explore the clinical value of fractional flow reserve(FFR) in the evaluation of the support function of side branch in the patients with bifurcation lesion.Methods From January 2013 to September 2014,168 patients with bifurcation lesions were divided into test group and control group according to the random number table in the First Hospital of Nanjing,each of 84 cases.Test group:When the stenting was placed in the main branch,the FFR of the side branch was then measured.If FFR<0.80,according to the situation underwent balloon angioplasty or stent implantation;If FFR≥0.80,then left untreated.Control group:When the stenting was placed in the main branch,the percentage diameter stenosis(DS%) of side branch was then measured by quantitative coronary aniography(QCA).If DS%≥75%,according to the situation underwent balloon angioplasty or stent implantation;If DS%0.05);The dosage of contrast agent in the test group was less than that in the control group[(58.5±12.8)mlvs. (79.7±9.3)ml](P<0.05);The number of stent implantation in the test group was less than that in the control group[102vs. 145](P<0.05);The incidence of MACE in the test group was lower than that in the control group[14.3%vs. 27.4%](P<0.05).Conclusions FFR can accurately assess the function of the side branch vessels, which is helpful to select the appropriate intervention strategies of bifurcation lesions, reduce unnecessary stent implantation, and reduce the dosage of contrast agent.
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