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目的明确本次甲肝暴发的原因。方法采用病例对照研究方法,根据预调查结果,设计统一调查表,对14岁儿童进行调查,同时采集血清检测甲肝抗-IgM抗体,以抗HAV-IgM抗体阳性儿童为病例组,以抗HAV-IgM抗体阴性且HAV-IgG抗体阴性的儿童为对照组。将调查结果用EPIDATA软件建立数据库,并用SPSS13.0进行分析。结果本次暴发历时2个常见甲肝潜伏期,共感染20例幼儿。统计结果显示,经常去幼儿园玩耍和与首发病例共餐及经常去首发病例家玩耍为本次感染的主要危险因素(P<0.001)。结论本次为典型的人传人连续性传播,患病儿童对幼儿园玩具的污染导致甲肝病毒的播散,而儿童没有良好的卫生习惯如饭前不洗手、喝生水等是其得以发病的重要条件。
Objective To clarify the causes of this outbreak of hepatitis. Methods A case-control study was conducted. According to the results of the pre-investigation, a unified questionnaire was designed to investigate the 14-year-old children. At the same time, serum anti-HG-IgM antibodies were collected to detect anti-HAV- Children with IgM antibody negative and HAV-IgG antibody negative were the control group. The survey results using EPIDATA software to establish a database, and SPSS13.0 for analysis. Results The outbreak lasted two common hepatitis A incubation period, a total of 20 cases of young children. Statistics show that frequent kindergarten play and dinner with the first case and frequent debut cases play a major risk factor for this infection (P <0.001). Conclusion This is a typical transmission of continuous transmission of people, children infected with kindergarten toys led to the dissemination of hepatitis A virus, and children do not have good hygiene practices such as not washing hands before meals, drink raw water is its incidence is important condition.