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目的:探讨中西医结合治疗急性脑梗死的临床疗效。方法:62例急性脑梗死患者随机分成治疗组(n=31)和对照组(n=31)。两组患者均给予西医常规治疗,同时给予尤瑞克林,治疗组在上述治疗基础上加用中药苦碟子注射液,疗程均为14 d。观察并比较两组患者在治疗前后及治疗后90 d的NIHSS评分情况,同时分别比较治疗后90 d两组患者的MRS评分在2分以下、Barthel指数大于80分者所占的比例。结果:①治疗后两组患者的NIHSS评分均有所下降(P<0.05),尤以治疗组下降更加显著,但治疗组评分与对照组比较差异无统计学意义(P>0.05);治疗后90 d两组患者的NIHSS评分均显著降低(P<0.05或P<0.01),且治疗组评分较对照组降低更加明显(P<0.05)。②治疗后90 d,治疗组和对照组患者中MRS评分在2分以下者所占的比例分别为78.32%、67.28%,两组比较差异具有统计学意义(P<0.05)。③治疗后90 d,治疗组和对照组患者中Barthel指数大于80分者所占的比例分别为81.32%、60.58%,两组比较差异具有统计学意义(P<0.05)。结论:以清热解毒中药苦碟子注射剂结合西药尤瑞克林治疗急性脑梗死具有较好的疗效,能有效改善患者的神经功能缺损评分,提高患者的生活能力。
Objective: To explore the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of acute cerebral infarction. Methods: Sixty-two patients with acute cerebral infarction were randomly divided into treatment group (n = 31) and control group (n = 31). Both groups were given routine western medicine, while giving uracil, the treatment group in the above treatment based on the use of Chinese medicine Kakudo injection, treatment were 14 d. The NIHSS scores of both groups before and after treatment and 90 days after treatment were observed and compared. The MRS scores of two groups at 90 d after treatment were below 2, and the Barthel index was greater than 80. Results: The NIHSS scores of both groups decreased after treatment (P <0.05), especially in the treatment group, but there was no significant difference between the treatment group and the control group (P> 0.05). After treatment The NIHSS scores of the two groups were significantly decreased on the 90th day (P <0.05 or P <0.01), and the score of the treatment group was significantly lower than that of the control group (P <0.05). ② At 90 days after treatment, the proportion of patients with MRS score less than 2 in treatment group and control group were 78.32% and 67.28% respectively, with significant difference between the two groups (P <0.05). ③ At 90 days after treatment, the proportion of patients with Barthel index greater than 80 in treatment group and control group were 81.32% and 60.58%, respectively. There was significant difference between the two groups (P <0.05). Conclusion: The Qingrejiedu Kudiezi injection combined with western medicine Yrekkarin treatment of acute cerebral infarction has a good effect, can effectively improve the patient’s neurological deficit score and improve patients’ ability to live.