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目的探究江苏省昆山市1993—2014年白血病死亡趋势。方法江苏省昆山市1993—2014年白血病死亡病例来源于昆山市历年的死因监测;计算历年白血病粗死亡率,以及中国2000年人口年龄构成标化的死亡率(age standardized rate,ASR);使用年度变化百分比(annual percentage change,APC)及其95%CI评价白血病死亡率在年份之间变化趋势。结果江苏省昆山市1993—2014年期间白血病死亡总例数为570例,占全肿瘤比例2.19%;其中男312例,女258例。白血病粗死亡率在男女合计(APC=1.5,95%CI:0.0~3.0,P=0.0604)、男性人群(APC=0.8,95%CI:-0.6~2.2,P=0.2756)及女性人群中(APC=2.7,95%CI:0.0~5.4,P=0.0622)均没有明显的变化趋势。1993—2014年白血病中标死亡率在男女合计(APC=1.5,95%CI:0.0~3.0,P=0.0604)、男性(APC=-0.7,95%CI:-2.4~1.0,P=0.4087)以及女性(APC=0.4,95%CI:-2.3~3.1,P=0.7612)人群中均没有明显变化趋势。结论虽然白血病死亡率变化趋势不明显,但是因白血病死亡的例数逐年增加,在全人群中开展白血病预防控制十分必要。
Objective To investigate the mortality of leukemia in Kunshan City, Jiangsu Province from 1993 to 2014. Methods The death of leukemia in Kunshan City, Jiangsu Province, from 1993 to 2014, was derived from the monitoring of the cause of death in Kunshan City in the past years. The crude mortality rate of leukemia and the age standardized rate (ASR) of population age in China in 2000 were calculated. The annual percentage change (APC) and its 95% CI were used to evaluate the trend of leukemia mortality between years. Results A total of 570 leukemia death cases were reported in Kunshan City, Jiangsu Province from 1993 to 2014, accounting for 2.19% of the total tumor size. There were 312 males and 258 females. The crude leukemia mortality rate was significantly higher in both men and women (APC = 1.5, 95% CI: 0.0-3.0, P = 0.0604), in the male population (APC = 0.8,95% CI -0.6 to 2.2, P = 0.2756) APC = 2.7, 95% CI: 0.0 ~ 5.4, P = 0.0622) showed no obvious trend. The successful death rate of leukemia in 1993-2014 was statistically significant (P0.05). Male and female (APC = -0.7, 95% CI: -2.4 ~ 1.0, P = 0.4087) Women (APC = 0.4, 95% CI: -2.3 to 3.1, P = 0.7612) no significant trend in the population. Conclusions Although the change trend of leukemia mortality is not obvious, the number of leukemia death cases is increasing year by year, so it is necessary to carry out leukemia prevention and control in the whole population.