Effects of oxaliplatin on DNA condensation

来源 :中国科学：物理学、力学、天文学英文版 | 被引量 : 0次 | 上传用户：birdobird

【摘要】

：

In this paper the interactions between DNA and anti-cancer drug oxaliplatin were investigated by using magnetic tweezers.The dynamics of DNA condensation due to

【作者】

：

JU HaiPeng ZHANG HongYan LI We

【机构】

：

BeijingNationalLaboratoryforCondensedMatterPhysicsandKeyLaboratoryofSoftMatterPhysics

【出处】

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中国科学：物理学、力学、天文学英文版

【发表日期】

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2014年11期

【关键词】

：

奥沙利铂 DNA 凝聚相互作用抗癌药缩合 DNA condensation shortening torsion helpful constraint c

【基金项目】

：

This work was supported by the National Natural Science Foundation of China （Grant Nos. 11104341 and 11274374） and the National Basic Re- search Program of China （Grant No. 2013CB837200）.

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In this paper the interactions between DNA and anti-cancer drug oxaliplatin were investigated by using magnetic tweezers.The dynamics of DNA condensation due to oxaliplatin was traced under various forces.It is found that torsion constraint in DNA enhance

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Effects of oxaliplatin on DNA condensation

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