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文中介绍了一种由层层自组装方法制备的聚电解质微囊。该微囊作为一种全新的给药系统,其显著的优越性是能够在纳米范围内对微囊的大小、组成、结构、形态和囊壁厚度进行精确的控制,且通过不同囊材组合能够制得各种刺激感应型的释药体系,如pH、盐、光、磁、葡萄糖感应型及生物降解型等。它们将在未来的药物控释领域发挥重要作用。现就各种刺激感应型的聚电解质微囊进行综述。
In this paper, a polyelectrolyte microcapsule prepared by the layer self-assembly method is introduced. As a new drug delivery system, the microcapsules have the remarkable advantage of being able to precisely control the size, composition, structure, morphology and wall thickness of microcapsules in the nanometer range, and by combining different capsule materials, Produced a variety of stimuli-responsive drug delivery system, such as pH, salt, light, magnetism, glucose-responsive and biodegradable. They will play an important role in the future of drug controlled release. Now on a variety of stimuli-responsive polyelectrolyte microcapsules are reviewed.