论文部分内容阅读
被动性体温升高初期血浆皮质醇浓度减低,但当体温超过33.3℃时,皮质醇分泌反而增加。本文研究了8例男性受试者在高热环境下,轻度活动引起体温迅速升高时的血浆生长激素(GH)和皮质醇的变化。 8名健康男性18～29岁的受试者,实验先在湿球室温35.8±0.5℃,干球室温51.0±1.0℃的室内进行18分钟,然后室温降至湿球室温31.3±0.5℃,干球室温47.0±1.0℃受试者上下30厘米高的凳子。前20分钟的速度是每分钟22个来回(按节拍器速度),在此期间消耗的能量是以前多次预试验所测定的最大氧张力的44.4±5.6％。这样的运动强度不会引起血浆皮质醇增加,但可刺激GH分泌。受试者继续在热室内作这样的运动达60分钟,使体温尽可能维持在38.8℃(自身对照性高热),同时每隔10分钟抽取血样品,测定皮质醇和GH的含量。另外,利用微量血球比积
Passive body temperature decreased early plasma cortisol concentration decreased, but when the body temperature exceeds 33.3 ℃, the cortisol secretion increased instead. In this paper, we studied the changes of plasma growth hormone (GH) and cortisol in eight male subjects under the conditions of high fever and mild temperature rise caused by rapid increase of body temperature. 8 healthy men 18 to 29 years old subjects, the experiment first wet room temperature 35.8 ± 0.5 ℃, dry room temperature 51.0 ± 1.0 ℃ for 18 minutes indoors, then the room temperature dropped to room temperature wet 31.3 ± 0.5 ℃, dry Ball room temperature 47.0 ± 1.0 ℃ subjects up and down 30 cm high stool. The first 20 minutes at a speed of 22 rounds per minute (at metronome velocities) during which energy was consumed was 44.4 ± 5.6% of the maximum oxygen tension as determined by previous pre-tests. Such exercise intensity does not cause an increase in plasma cortisol, but can stimulate GH secretion. Subjects continued to do this exercise in the hot chamber for 60 minutes, keeping the body temperature at 38.8 ° C (self-control hyperthermia), while taking blood samples every 10 minutes to determine cortisol and GH levels. In addition, the use of trace hematocrit