法莫替丁与雷尼替丁治疗十二指肠溃疡的比较

• 作 者: 王根生 顾同进 赵询梅 项平
• 机 构: 华东医院,华东医院,华东医院,华东医院 上海 200040,上海 200040,上海 200040,上海 200040
• 出 处: 新药与临床
• 发表日期: 1993年01期
• 关键词: 十二指肠溃疡 法莫替丁 治疗应用 溃疡愈合 胃镜复查 雷尼 有效例数 药物疗法 溃疡 胃镜

70例活动性十二指肠溃疡(DU)患者分2组,38例每晚服用40mg法莫替丁(Fam),男29例,女9例,平均年龄44±12a。32例每晚服300mg雷尼替丁(Ran),男25例,女7例,平均年龄39±8a。经4wk治疗后胃镜复查,2组溃疡愈合例数分别为23例(60％)和20例(62％),无显著差异。但Ran组中6例(19％)无效,而Fam组中38例(100％)有效。2组有效例数比较有非常显著差异P<0.01。

Seventy patients with active duodenal ulcer (DU) were divided into two groups. 38 patients took Famotidine 40 mg per night, 29 males and 9 females, with an average age of 44 ± 12 years. Thirty-two patients received 300 mg of ranitidine (Ran) per night, 25 males and 7 females, with an average age of 39 ± 8 a. Gastroscopy after 4wk treatment, the two groups of ulcer healing cases were 23 cases (60%) and 20 cases (62%), no significant difference. However, 6 (19%) patients in the Ran group were ineffective, compared with 38 (100%) in the Fam group. Two groups of effective number of cases there are very significant differences P <0.01.