论文部分内容阅读
目的观察孕激素治疗早孕黄体功能不足的临床效果。方法 102例确诊早孕黄体功能不足的患者,根据入院时间先后顺序分为观察组和对照组,各61例。观察组患者根据孕酮水平分别给予不同剂量的黄体酮注射液肌内注射和黄体酮胶囊口服,对照组患者给予中成药保胎灵口服治疗。观察两组患者胚胎发育、治疗前后激素水平。结果观察组保胎成功率为88.52%,明显高于对照组的21.31%(P<0.01);观察组血清孕酮(P)、雌二醇(E_2)水平均明显高于对照组(P<0.05)。结论早期、足量应用孕激素治疗有助于改善黄体功能不足激素水平,促进胚胎正常发育,降低流产率,改善母婴预后。
Objective To observe the clinical efficacy of progesterone in the treatment of early pregnancy corpus luteum insufficiency. Methods A total of 102 patients diagnosed as early pregnancy with corpus luteum insufficiency were divided into observation group and control group according to the order of admission, each of 61 cases. Patients in the observation group were given different dosages of progesterone intramuscular injection and progesterone capsules orally according to progesterone levels, while those in the control group were treated with Baoshengling, a proprietary Chinese medicine. The embryo development in both groups was observed before and after treatment. Results The success rate of miscarriage in observation group was 88.52%, which was significantly higher than that in control group (21.31%, P <0.01). The levels of serum progesterone and estradiol in observation group were significantly higher than those in control group (P < 0.05). Conclusion Early application of progestin in sufficient quantity will improve the level of hormone deficiency in corpus luteum, promote the normal embryo development, reduce the abortion rate and improve the prognosis of maternal and infant.