论文部分内容阅读
目的探讨血清前白蛋白与谷丙、谷草转氨酶在新生儿高胆红素血症的临床应用。方法对120例高胆红素血症患儿分别于治疗前、后行血清谷丙转氨酶(ALT),谷草转氨酶(AST)及前白蛋白含量测定。结果 120例患儿治疗前血清ALT、AST、前白蛋白异常率分别为35.00%、40.00%、55.83%,血清前白蛋白与ALT、AST异常率相比较差异均有统计学意义(P均<0.01)。且治疗前后血清前白蛋白的变化与谷丙转氨酶(ALT)、谷草转氨酶(AST)的变化相比差异均有统计学意义(P均<0.01)。结论新生儿高胆红素血症患儿可产生不同程度的肝损伤。血清前白蛋白可作为检测高胆红素血症患儿肝细胞功能的指标。
Objective To investigate the clinical application of serum prealbumin, alanine and aspartate aminotransferase in neonatal hyperbilirubinemia. Methods 120 cases of hyperbilirubinaemia were measured before and after treatment of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and prealbumin content determination. Results The serum levels of ALT, AST and prealbumin in 120 children before treatment were 35.00%, 40.00% and 55.83%, respectively. The differences of serum prealbumin and ALT and AST were statistically significant (all P < 0.01). The changes of serum prealbumin before and after treatment were significantly different from those of ALT and AST (all P <0.01). Conclusion Newborns with hyperbilirubinemia can produce different degrees of liver damage. Pre-serum albumin can be used as an indicator of hepatocyte function in children with hyperbilirubinemia.