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目的:评价洛赛克、羟氨苄青霉素二联疗法对幽门螺杆菌(HP)相关性消化性溃疡的疗效。方法:将83例HP阳性的胃和十二脂肠溃疡患者按就诊顺序分为A、B两组。A组43例,每次口服洛赛克20mg,1天1次,21天,羟氨苄青霉素500mg,1天3次,14天。B组40例,在A组服药的基础上再给甲硝唑400mg,1天3次,14天。结果:两组溃疡愈合率分别为93.0%、95.0%,HP消除率分别为81.4%、85.0%。结论:两组溃疡治愈率和HP消除率差异无显著性(P>0.05),B组副作用明显高于A组(P<0.05)。
Objective: To evaluate the efficacy of dicloxacillin and diclofenac in the treatment of Helicobacter pylori (HP) -related peptic ulcer. Methods: 83 patients with HP-positive gastric and 12 patients with intestinal ulcer according to the order of treatment is divided into A, B two groups. A group of 43 patients, each time oral Losec 20mg, 1 day 1, 21 days, amoxicillin 500mg, 1 day 3 times, 14 days. Forty cases in group B were given metronidazole 400 mg three times a day for 14 days. Results: The healing rates of ulcer in both groups were 93.0% and 95.0%, respectively. The HP eradication rates were 81.4% and 85.0% respectively. Conclusion: There was no significant difference between the two groups in the cure rate of ulcer and the elimination rate of HP (P> 0.05). The side effects in group B were significantly higher than those in group A (P <0.05).