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目的观察中西医结合治疗小儿厌食症的临床疗效及其安全性。方法将114例患儿按照随机数字表法随机分为对照组和治疗组,治疗组采用中西医结合治疗,对照组仅给予西药治疗。2组疗程均为2周。对比2组的临床疗效、主要症状积分、血锌与血红蛋白含量及不良反应发生情况。结果治疗组总有效率(96.55%)显著高于对照组(80.36%),差异有统计意义(P<0.05);2组患儿治疗后血锌与血红蛋白含量均较治疗前显著升高,差异有统计意义(P<0.05),且治疗组升高幅度优于对照组,差异有统计意义(P<0.05);2组治疗后食量减少、面色少华、大便失调症状积分较治疗前显著下降,差异有统计意义(P<0.05),且治疗组下降幅度优于对照组,差异有统计意义(P<0.05)。2组在治疗期间均未发生明显不良反应。结论中西医结合治疗小儿厌食症临床疗效显著,安全可靠,值得临床推广应用。
Objective To observe the clinical efficacy and safety of Integrative Chinese and Western medicine treatment of children with anorexia. Methods A total of 114 children were randomly divided into control group and treatment group according to the random number table method. The treatment group was treated with combination of TCM and western medicine, while the control group was treated with western medicine alone. The two groups were treated for 2 weeks. The clinical efficacy, main symptom scores, blood zinc and hemoglobin content and adverse reactions were compared between the two groups. Results The total effective rate (96.55%) in the treatment group was significantly higher than that in the control group (80.36%), the difference was statistically significant (P <0.05); The levels of blood zinc and hemoglobin in the two groups were significantly higher than those before treatment (P <0.05), and the treatment group than the control group, the difference was statistically significant (P <0.05); after treatment, food intake decreased, Shaohua, stool disorders symptom scores than before treatment decreased significantly , The difference was statistically significant (P <0.05), and the treatment group was better than the control group, the difference was statistically significant (P <0.05). No significant adverse reactions occurred in the two groups during the treatment. Conclusion Integrative medicine treatment of children with anorexia clinical efficacy was significant, safe and reliable, it is worth clinical application.