Engineering personalized neural tissue using functionalized transcription factors

• 作 者: Stephanie M.Willerth
• 机 构: Department of Mechanical Engineering and Division of Medical Sciences,University of Victoria,Centre
• 出 处: Neural Regeneration Research
• 发表日期: 2016年10期
• 关键词: restore traumatic pluripotent cascade neuronal desired transfection endogenous d

Diseases and disorders of the central nervous system often require significant interventions to restore lost function due to their complexity.Examples of such disorders include Parkinson’s disease,Alzheimer’s disease,multiple sclerosis,traumatic brain injury,and spinal cord injury.These diseases and disorders result from healthy cells being destroyed,which in turn causes dysfunction in the central nervous system.The death of these cells can trigger a cascade of events that affect the rest of the body,causing symptoms that

Diseases and disorders of the central nervous system often require significant interventions to restore lost function due to their complexity. Examples of such disorders include Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, traumatic brain injury, and spinal cord injury. These diseases and disorders result from healthy cells being destroyed, which in turn causes dysfunction in the central nervous system. The death of these cells can trigger a cascade of events that affect the rest of the body, causing symptoms that