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目的探讨孕妇外周静脉血及新生儿脐血激活素A(ACTA)水平与急性胎儿窘迫发病的关系。方法采用双抗体夹心ABC-ELISA法测定68例急性胎儿窘迫孕妇(实验组)和60例正常孕妇(对照组)产前、产后外周静脉血及新生儿脐血ACTA水平,分析ACTA与急性胎儿窘迫之间的相关性。结果实验组孕妇产前外周静脉血ACTA水平明显高于对照组孕妇(t=27.09,P<0.05)。两组孕妇产后外周静脉血及新生儿脐血ACTA水平比较差异无统计学意义(t=3.743,P>0.05;t=1.326,P>0.05)。结论孕妇外周静脉血ACTA水平变化在产前急性胎儿窘迫的监测中具有重要的临床意义及价值。
Objective To investigate the relationship between peripheral venous blood of pregnant women and neonatal cord blood activin A (ACTA) levels and the incidence of acute fetal distress. Methods ABC-ELISA method was used to detect the levels of PCNA in 68 pregnant women with acute fetal distress (experimental group) and 60 normal pregnant women (control group), and peripheral blood samples of neonates after birth and neonatal cord blood ACTA levels were analyzed with ACTA and acute fetal distress The correlation between. Results The antenatal peripheral venous blood ACTA level in experimental group was significantly higher than that in control group (t = 27.09, P <0.05). There was no significant difference in post-natal peripheral venous blood and neonatal ACTA levels between the two groups (t = 3.743, P> 0.05; t = 1.326, P> 0.05). Conclusion The changes of peripheral blood levels of ACTA in pregnant women have important clinical significance and value in the monitoring of prenatal acute fetal distress.