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丙卡特罗(Praooterol,I)为第三代新型拟肾上腺素类平喘药,对β_2受体选择性高。其速释片剂能迅速释放药物以达预期疗效。本文采用小杯溶出转篮法拟对自制丙卡特罗速释片体外溶出度做初步考察。1 仪器、试剂和样品1.1 仪器:HP1100型高压液相色谱仪(美国惠普公司);TDP 型单冲式压片机(上海天和制药机械厂);
Pradererol (I) is the third generation of novel adrenergic antiasthmatic agents, which are highly selective for β_2 receptors. Its immediate release tablets rapidly release the drug for the desired effect. In this paper, small cup dissolution spin-basket method to make home-made Procaterol quick release tablets in vitro dissolution of make a preliminary study. 1 instruments, reagents and samples 1.1 Instruments: HP1100-based high-pressure liquid chromatography (Hewlett-Packard Company of the United States); TDP single-punch tablet press (Shanghai Tianhe Pharmaceutical Machinery Factory)