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Objective Explore the effect of Daicong solution on immune function for aged rat dementia model.Method Basal nuclei of 22 months old rat being destroyed by bilateral electrolytic method have been established animal dementia model of learning and memory function.Lymphocyte proliferation was tested by 3H TdR incorporation methods.Spleen cell producing antibody function was determined by spleen cell mediated red cell hemolysis method.Result Daicong solution has remarkably increased lymphocyte proliferation function,compared with model groups(P< 0.01).It has strengthened the producing antibody function of the spleen cell too,compared with model group (P< 0.01). Conclusion Daicong solution has marked increased functions of cellular and humoral immunity for dementia animal model. Which is heavier than that of Naofukang.