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本世纪以来许多国外学者报道了有关实验性肾炎的研究工作。自从 Masugi 在1933年改进实验方法以后,这方面的工作更得到进一步开展。许多学者用家兔和大白鼠产生了临床症状及组织学改变与人类肾小球性肾炎或肾病综合征极为近似的实验性肾炎。为了利用此种实验开展有关肾炎发病机制及药物疗效的研究,我们从62年10月开始用国产动物进行了制造实骇性肾炎的工作。鉴于目前国内尚缺乏此项实验工作的详细报道,国外关于慢性及亚急性实验性肾炎的报导也不多,故将此项工作总结报道于下:
Many foreign scholars have reported research on experimental nephritis since this century. Since Masugi improved experimental methods in 1933, this work has been further developed. Many scholars have used rabbits and rats to produce experimental nephritis with clinical symptoms and histological changes that closely resemble those of human glomerulonephritis or nephrotic syndrome. In order to use this type of experiment to carry out studies on the pathogenesis of nephritis and drug efficacy, we began to use homemade animals to manufacture SSG from October 62. In view of the lack of detailed reports on the experimental work in the country, there are not many reports on chronic and subacute experimental nephritis in foreign countries. Therefore, this work is summarized in the following report: