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[目的]探讨海宁市恶性肿瘤流行特征及变化趋势,为制定肿瘤预防控制策略与措施提供依据。[方法]应用海宁市肿瘤登记系统资料,对各类恶性肿瘤发病情况进行分析。[结果]1977～2006年全市恶性肿瘤发病率133.11/10万,中国标化发病率为93.10/10万,世界标化发病率为115.80/10万;构成比前5位依次为:肺癌、肝癌、胃癌、食管癌、大肠癌,占全部恶性肿瘤的68.02%。1992～2006年与1977～1991年恶性肿瘤发病率上升了34.51%(P<0.01);上升幅度较大的恶性肿瘤有:胰腺癌、脑肿瘤、膀胱癌、乳腺癌、肺癌、大肠癌;与此同时,食管癌、宫颈癌则有所下降。[结论]近年来恶性肿瘤发病率呈明显上升态势,癌症发病谱发生了较大变化,提示今后肿瘤防治工作的重点应放在肺癌及消化系统恶性肿瘤方面。
[Objective] To investigate the epidemiological characteristics and trends of malignant tumors in Haining City and provide evidence for the development of strategies and measures for cancer prevention and control. [Methods] The data of Haining tumor registration system were used to analyze the incidence of various malignant tumors. [Results] The incidence of malignant tumors in the whole city was 133.11 / 100,000 in 1977-2006, the incidence rate of standardization in China was 93.10 / 100,000 and the incidence of standardization in the world was 115.80 / 100,000. The top five components were lung cancer, liver cancer , Gastric cancer, esophageal cancer, colorectal cancer, accounting for 68.02% of all malignant tumors. The incidence of malignant tumors increased by 34.51% (P <0.01) from 1992 to 2006 and from 1977 to 1991; the malignant tumors that increased greatly were pancreatic cancer, brain tumor, bladder cancer, breast cancer, lung cancer and colorectal cancer; At the same time, esophageal cancer, cervical cancer is declining. [Conclusion] In recent years, the incidence of malignant tumors showed a clear upward trend, and the incidence of cancer has undergone major changes, suggesting that future cancer prevention and treatment should focus on lung cancer and digestive system malignancies.