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目的:评价肥厚型心肌病(HCM)患者的左房射血力并探讨其意义。方法:使用超声技术测量56例HCM患者和33例正常对照的左房射血力,根据HCM患者左室舒张功能受损程度不同依次分为Ⅰ、Ⅱ、Ⅲ、Ⅳ组。结果:左房射血力,Ⅱ、Ⅲ组高于正常对照组、I组和Ⅳ组,其中Ⅱ组又高于Ⅲ组(P均<0.05);肺静脉口A波峰值流速,Ⅱ、Ⅲ、Ⅳ组明显高于正常对照组及I组,其中Ⅱ组又高于Ⅳ组(P均<0.05);左房泵血量,Ⅱ、Ⅲ组高于正常对照组(P均<0.05)。结论:多数肥厚型心肌病患者左房射血力代偿性增加,左房射血力受心室顺应性等因素影响。
Objective: To evaluate the left atrial ejection force in patients with hypertrophic cardiomyopathy (HCM) and to explore its significance. Methods: Left atrial ejection force was measured in 56 patients with HCM and 33 normal controls using ultrasound. According to the degree of left ventricular diastolic dysfunction in HCM patients, they were divided into groups Ⅰ, Ⅱ, Ⅲ and Ⅳ. Results: Left atrium ejection force was higher in group Ⅱ and Ⅲ than in control group, group I and group Ⅳ, and group Ⅱ was higher than group Ⅲ (all P <0.05) Ⅳ group was significantly higher than the normal control group and I group, which was higher in group Ⅱ than in group Ⅳ (P <0.05); left atrial pump blood volume, Ⅱ, Ⅲ group than in normal control group (P all <0.05). Conclusion: The majority of patients with hypertrophic cardiomyopathy left ventricular ejection compensatory increase in left atrial ejection force by ventricular compliance and other factors.