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作者应用海螺状与螺旋球形记忆合金血管栓塞器(简称NT-海球栓)对肾癌侧肾动脉进行栓塞。对7例手术切除的肾癌标本进行巨检和光镜观察,结果显示:(1)4例靶肾动脉的改变,主要发生在NT-海球栓的扩卡部,该栓塞段动脉壁呈扩张状态,因NT-海球栓的机械压迫致内皮细胞萎缩变性或坏死,内弹性腆断裂或消失。中膜内干滑肌细胞萎缩变性,其弹性纤维断裂和减少。外膜无明显改变。有2例附加明胶海绵栓塞剂,在肾动脉内有血栓形成,伴有动脉炎;(2)7例靶肾癌组织的改变:肾组织主要显示缺血性萎缩变性坏死,其变性的严重程度依次是:近曲小管、远曲小管、肾小体。有5例发生1～2处梗死灶。靶肾癌组织大部分发生坏死。残存的癌组织部分存活、部分变性。
The authors used conch-shaped spiral ball memory alloy vascular embolization device (referred to as NT-sea bolt) on the renal artery renal artery embolization. Seven cases of resected renal cell carcinoma were examined by macroscopic examination and light microscopy. The results showed that: (1) The changes of the target renal artery in 4 cases mainly occurred in the card-expanding part of NT-SE, and the artery wall of the embolized segment was dilated State, due to mechanical compression NT-ball plug endothelial cell atrophy degeneration or necrosis, within the elastic break or disappear. Mesangial atrophy of dry muscle cells, the elastic fibers rupture and reduce. Outer membrane no significant change. There are 2 cases of additional gelatin sponge embolization agent, thrombosis in the renal artery, accompanied by arteritis; (2) 7 cases of target renal cancer tissue changes: renal tissue mainly shows ischemic atrophic necrosis, the severity of degeneration Followed by: proximal convoluted tubule, distal convoluted tubule, renal body. In 5 cases 1 or 2 infarcts occurred. Most of the target renal cancer tissue necrosis. Surviving part of cancer survived, partially degenerated.