Stereoselective Synthesis of 1,3-Enynylstannanes via Palla-dium Catalyzed Cross-Coupling Reactions o

• 作 者: 蔡明中 章荣立 赵红
• 机 构: Institute of Chemistry, Jiangxi Normal University, Nanchang, Jiangxi 330027, China,Institute of Chem
• 出 处: Chinese Journal of Chemistry
• 发表日期: 2004年12期
• 关键词: silica conjugated moiety readily hydrolyzed methoxy hexane eluting starting diph

Based on the different reactivity of stannyl and bromo groups, (Z)-α-bromovinylstannanes can undergo the cross-coupling reaction with alkynyl Grignard reagents in the presence of tetrakis(triphenylphosphine)palladium(0) catalyst in THF at room temperature to afford stereoselectively 1,3-enynylstannanes in good yields.

Based on the different reactivity of stannyl and bromo groups, (Z) -α-bromovinylstannanes can underwent the cross-coupling reaction with alkynyl Grignard reagents in the presence of tetrakis (triphenylphosphine) palladium (0) catalyst in THF at room temperature to afford stereoselectively 1,3-enynylstannanes in good yields.