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目的:探讨急性农药中毒采用血液净化方案治疗的临床效果。方法:本次研究选择的对象共40例,均为我院2010年5月至2012年5月收治的急性农药中毒患者,随机按观察组和对照组各20例划分,对照组采取常规救治方案加血液灌流治疗,观察组在此基础上加用连续性血液滤过行血液净化治疗,回顾相关临床资料。结果:观察组20例中,治愈19例,占95%;死亡1例,占5%。对照组20例中,治愈17例,占85%,死亡3例,占15%。治愈率及死亡率组间比较有统计学差异(P<0.05)。观察组昏迷时间、ChE活性恢复时间、呼吸机使用时间、住院时间明显少于对照组,差异均有统计学意义(P<0.05)。结论:急性农药中毒采用血液灌流联合连续性血液滤过行血液净化治疗,可显著提高临床抢救成功率,缩短住院时间,改善临床症状,为患者生命安全提供了强有力的保障。
Objective: To investigate the clinical effect of blood purification in acute pesticide poisoning. Methods: A total of 40 subjects were selected in this study, all of whom were acute pesticide poisoning patients who were admitted to our hospital from May 2010 to May 2012. They were randomly divided into observation group (20 cases) and control group (20 cases), and control group Plus hemoperfusion treatment, the observation group on the basis of continuous hemodilution with blood purification treatment, review the relevant clinical data. Results: In the observation group of 20 cases, 19 cases were cured, accounting for 95%; 1 case died, accounting for 5%. Control group of 20 cases, 17 cases were cured, accounting for 85%, 3 died, accounting for 15%. There was a significant difference between cure rate and mortality (P <0.05). Observation group coma time, ChE activity recovery time, ventilator use time, hospitalization was significantly less than the control group, the difference was statistically significant (P <0.05). Conclusion: Acute pesticide poisoning using blood perfusion combined with continuous hemofiltration blood purification treatment can significantly improve the success rate of clinical rescue, shorten the hospital stay, improve clinical symptoms, provide a strong guarantee for the life safety of patients.