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鼻病毒是小 RNA病毒，无包膜，属于小核糖核酸病毒科家族，包括 A、B、C 三种，有超过100种抗原性不同的血清型。40％的慢性阻塞性肺疾病（ COPD）急性加重与病毒感染有关，且大部分为鼻病毒。鼻病毒感染COPD患者可引起气道炎症反应和气道微生物的变化。对于鼻病毒的治疗，目前尚无特效的抗病毒药物。研究者主要将注意力集中在鼻病毒疫苗的研制上，虽然进展不大，但其依然是个有前途的研究方向。“,”Rhinovirus is no-envelope and small RNA virus, which belongs to the small RNA virus family,and includes A,B,C three kinds and more than 100 kinds of different serotypes.40% of acute exac-erbation of chronic obstructive pulmonary disease ( COPD) is related to viral infections,mostly rhinovirus. Rhinovirus can cause changes of airway inflammation and airway microorganisms in patients with COPD . There is no special effect of antiviral drugs for the treatment of rhinovirus so far , and the researchers are mostly focused on rhinovirus vaccine.Although there is no considerable progress up till now,it still is a prom-ising research direction.