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随着糖尿病患病率的增加,糖尿病肾病(DN)的患病率也逐年增加,DN占糖尿病病人总数的10%～21%。DN已成为终末期肾衰竭(ESRF)的主要病因。ESRF所需治疗给病人和国家都带来了严重的经济负担。目前,尚无针对DN的特效治疗,如何防止DN的发生、发展,防止ESRF的发生,合理的综合治疗至关重要,如严格控制高血糖;抗高血压药物ACEI、ARBs和螺内酯等的合理应用;他汀类药物和胰岛素增敏剂等的应用;适当限制蛋白质和钠盐的摄入,戒烟、戒酒、减肥等生活方式的干预对DN也非常重要。
As the prevalence of diabetes increases, the prevalence of diabetic nephropathy (DN) has also increased year by year, with DN accounting for 10% to 21% of the total number of diabetic patients. DN has become the leading cause of end-stage renal failure (ESRF). The treatment required for ESRF poses a serious financial burden on both the patient and the country. At present, there is no specific treatment for DN, how to prevent the occurrence and development of DN and prevent the occurrence of ESRF, and reasonable comprehensive treatment is crucial, such as strict control of hyperglycemia; rational use of anti-hypertensive drugs such as ACEI, ARBs and spironolactone ; Statins and insulin sensitizers and other applications; appropriate restrictions on protein and sodium intake, quit smoking, abstinence, diet and other lifestyle interventions for DN is also very important.