唐山地区儿童病毒性腹泻分子流行病学调查

• 作 者: 余亮科 赵文喆 高捷 张双 张志坤
• 机 构: 河北联合大学附属医院,唐山市卫生局医教处,唐山市妇幼保健院感染性疾病科,唐山市疾病控制中心,
• 出 处: 中国妇幼保健
• 发表日期: 2011年34期
• 关键词: 腹泻 腹泻病毒 好发年龄 好发时间

目的:探讨唐山地区2007年1月～2010年12月儿童腹泻发病现状,并对腹泻病毒进行流行病学调查分析。方法:随机抽取唐山地区2007年1月～2010年12月腹泻儿童1 100例资料。所有患儿均经过粪便检查,采用多种方法分析常见病原菌及好发时间。结果:1 100例儿童中,轮状病毒582例,占52.91%;诺如病毒258例,占23.45%;札如病毒89例,占8.09%;星状病毒52例,占4.73%;腺病毒119例,占10.82%。其中轮状病毒在10～12月及1月高发,诺如病毒为7～9月高发,其他病毒在各时间段均有检出。结论 :唐山地区儿童腹泻的好发年龄为5岁以下。引发腹泻的主要病毒为轮状病毒和诺如病毒,星状病毒、札如病毒及腺病毒也较常见。不同病毒有其流行病的高峰期,轮状病毒为秋冬季,诺如病毒为夏秋季,其余病毒无明显季节分布。

Objective: To investigate the incidence of childhood diarrhea in Tangshan from January 2007 to December 2010, and to investigate the epidemiology of diarrhea virus. Methods: A total of 1,100 children with diarrhea in Tangshan from January 2007 to December 2010 were randomly selected. All children were stool examination, using a variety of methods to analyze common pathogens and the time of onset. Results: Of the 100 children, 582 cases were rotavirus (52.91%), 258 cases were Norovirus (23.45%), 89 cases were Sapporo virus (8.09%), 52 cases were Astrovirus (4.73%), adenovirus 119 cases, accounting for 10.82%. Rotavirus in which 10 to 12 months and January high incidence of Norovirus is high from July to September, other viruses were detected in each time period. Conclusion: The prevalence of diarrhea in children in Tangshan is less than 5 years old. The major viruses that cause diarrhea are rotavirus and Norovirus, and astroviruses, Sapporo virus and adenovirus are more common. Different viruses have their peak period, rotavirus is autumn and winter, norovirus is summer and autumn, the rest of the virus no obvious seasonal distribution.