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目的探讨双水平气道正压无创通气(BiPAP)治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的疗效及护理体会。方法选择我科2007年至2009年住院的120例COPD合并Ⅱ型呼吸衰竭患者,在常规治疗的基础上应用Bi-PAP治疗,观察治疗前后动脉血pH、动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)及血氧饱和度(SaO2)的变化。结果治疗后4、8 h及脱机后2 h,患者动脉血pH、PaO2、PaCO2及SaO2较治疗前均有显著变化(P<0.05)。结论Bi-PAP治疗COPD合并Ⅱ型呼吸衰竭,可显著改善患者缺氧和二氧化碳潴留,同时需加强护理,指导患者有效配合治疗。
Objective To investigate the efficacy and nursing experience of bi-level positive airway pressure noninvasive ventilation (BiPAP) in the treatment of chronic obstructive pulmonary disease (COPD) complicated with type Ⅱ respiratory failure. Methods A total of 120 COPD patients with type Ⅱ respiratory failure who were admitted to our hospital from 2007 to 2009 were enrolled in this study. Bi-PAP was used on the basis of routine treatment. The arterial blood pH, PaO2, Blood pressure of carbon dioxide (PaCO2) and oxygen saturation (SaO2) changes. Results The arterial blood pH, PaO2, PaCO2 and SaO2 were significantly changed (P <0.05) 4 and 8 hours after treatment and 2 hours after off-line. Conclusions Bi-PAP treatment of COPD with type Ⅱ respiratory failure can significantly improve the patients with hypoxia and carbon dioxide retention, and need to strengthen nursing to guide patients with effective treatment.