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目的探讨MRI联合DWI对强直性脊柱炎(AS)的诊断价值。资料与方法搜集经修订纽约标准确诊的31例AS病例和25例正常对照组,两组均行两侧骶髂关节常规MRI横断位和冠状位抑脂T2WI、T1WI联合SE/EPI扩散加权成像(DWI)横断位扫描(b值0,600 s/mm2),观察两组骶髂关节的信号改变,测量表观扩散系数(ADC)值并作统计学检验。结果 31例病例组中的24例双侧或单侧骶髂关节面下骨质抑脂T2WI呈高信号,29例DWI呈高信号,25例对照组骶髂关节面下骨质T2WI、DWI均呈等信号,测量ADC值,病变组为(0.993±0.169)×10-3mm2/s,对照组为(0.649±0.395)×10-3mm2/s,病变组ADC值明显高于对照组(t=4.14,P<0.001),两者间差异有统计学意义。结论 MRI联合DWI对AS早期诊断有重要的临床价值。
Objective To investigate the diagnostic value of MRI and DWI in ankylosing spondylitis (AS). Materials and Methods Collecting 31 cases of AS confirmed by New York standards and 25 cases of normal control group, routine MRI scan of both sides of sacroiliac joint and coronal fat suppression T2WI and T1WI combined with SE / EPI diffusion weighted imaging DWI) scan (b value: 0,600 s / mm2). The signal changes of sacroiliac joint were observed in two groups. Apparent diffusion coefficient (ADC) value was measured and statistically tested. Results Twenty-four patients in 31 cases had hyperosteogeny on T2WI and 29 cases on DWI. The T2WI and DWI in 25 cases of control group (0.993 ± 0.169) × 10-3mm2 / s in the control group and (0.649 ± 0.395) × 10-3mm2 / s in the control group, the ADC value in the lesion group was significantly higher than that in the control group (t = 4.14, P <0.001), the difference was statistically significant. Conclusion MRI combined with DWI has an important clinical value in the early diagnosis of AS.