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目的:观察地喹氯铵喷雾剂联合口腔溃疡散治疗小儿复发性阿弗他溃疡(RAU)临床疗效及不良反应。方法:选择RAU患儿102例,随机分为观察组和对照组各51例,观察组采用地喹氯铵喷雾剂加口腔溃疡散治疗,对照组采用碘甘油治疗,比较两组的临床疗效及不良反应。结果:观察组总有效48例(94.1%),对照组30例(58.8%);两组比较,差异非常显著(P<0.01)。两组均未发生明显不良反应。结论:地喹氯铵喷雾剂联合口腔溃疡散治疗小儿复发性口腔溃疡疗效优于碘甘油。
Objective: To observe the clinical efficacy and adverse reactions of deconazole combined with oral ulcer powder in the treatment of children with recurrent aphthous ulcer (RAU). Methods: A total of 102 children with RAU were randomly divided into observation group (51 cases) and control group (51 cases). The observation group was treated with dequalinium chloride spray plus oral ulcer powder, while the control group was treated with iodine glycerol. The clinical efficacy and Adverse reactions. Results: There were 48 cases (94.1%) in the observation group and 30 cases (58.8%) in the control group. The difference between the two groups was significant (P <0.01). No significant adverse reactions occurred in both groups. Conclusion: The combination of dequalinium chloride spray and oral ulcer powder in children with recurrent oral ulcer is superior to iodine glycerin.