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目的探讨硝酸异山梨酯对高龄慢阻肺并发慢性心衰的治疗价值。方法将218例高龄慢阻肺并发慢性心衰患者随机分为两组,对照组给予常规治疗,观察组在常规治疗基础上加用硝酸异山梨酯,比较两组治疗效果。结果观察组治疗总有效率为90.83%,明显高于对照组(P<0.01);治疗后观察组Pa O2、Pa CO2较对照组改善更明显(P<0.01);观察组治疗后心功能有明显改善(P<0.01);治疗后两组患者肺功能均有明显改善(P<0.01)。结论硝酸异山梨酯治疗高龄慢阻肺并发慢性心衰疗效显著,可有效改善患者的心功能,值得推广。
Objective To investigate the therapeutic value of isosorbide dinitrate on senile chronic obstructive pulmonary disease complicated with chronic heart failure. Methods A total of 218 elderly COPD patients with chronic heart failure were randomly divided into two groups. The control group was given routine treatment. The observation group was given isosorbide dinitrate on the basis of routine treatment. The therapeutic effect was compared between the two groups. Results The total effective rate of the observation group was 90.83%, which was significantly higher than that of the control group (P <0.01). PaO2 and PaCO2 in the observation group were improved more significantly than those in the control group (P <0.01) (P <0.01). After treatment, lung function of both groups was significantly improved (P <0.01). Conclusion Isosorbide dinitrate is effective in treating chronic obstructive pulmonary disease and chronic heart failure in elderly patients, which can effectively improve the patient’s cardiac function and is worth promoting.