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目的:探讨重症急性胰腺炎致全身炎症反应综合征的诊治经验。方法:回顾性分析142例重症急性胰腺炎致全身炎症反应综合征患者的临床资料。结果:142例患者治愈133例,死亡9例;其中发生多器官功能障碍综合征35例,死亡9例;假性胰腺囊肿26例,后期行囊肿内引流术治愈;胆源性胰腺炎74例,后期行手术治疗治愈。行腹腔灌洗引流、减压27例,血液透析6例次,胰床减压引流、坏死清除4例次,呼吸机机械支持治疗12例次。结论:早期进行有效的抗感染、容量复苏、抑酶、抑制炎症反应,可有效阻断全身炎症反应综合征向多器官功能障碍综合征的进程,保护重要脏器,提高重症急性胰腺炎的治愈率。
Objective: To investigate the diagnosis and treatment of systemic inflammatory response syndrome caused by severe acute pancreatitis. Methods: A retrospective analysis of 142 cases of severe acute pancreatitis caused by systemic inflammatory response syndrome in patients with clinical data. Results: Among the 142 patients, 133 cases were cured and 9 died. Among them, 35 cases developed multiple organ dysfunction syndrome, 9 cases died, 26 cases had pseudocapillary cysts, followed by cyst drainage, 74 cases had biliary pancreatitis Surgical treatment of the latter cured. Peritoneal lavage drainage, 27 cases of decompression, hemodialysis in 6 cases, decompression drainage in the pancreas, necrosis in 4 cases, ventilator mechanical support treatment in 12 cases. Conclusion: Early effective anti-infective capacity recovery, inhibition of the enzyme, inhibit the inflammatory response, which can effectively block the process of systemic inflammatory response syndrome to multiple organ dysfunction syndrome, protect important organs and improve the cure of severe acute pancreatitis rate.