Association of Polymorphisms in Angiotensin Ⅱ Receptor Genes with Aldosterone-producing Adenoma

• 作 者: 欧阳金芝 吴准 邢金春 闫永吉 张国玺 王保军 李宏召 马鑫
• 机 构: DepartmentofEndocrinology,DepartmentofUrology,DepartmentofUrology,DepartmentofUrology
• 出 处: 华中科技大学学报：医学英德文版
• 发表日期: 2011年3期
• 关键词: 单核苷酸多态性 血管紧张素 受体基因 醛固酮 TAQMAN探针 协会 中国汉族人群 等位基因频率 aldosterone-producing adenoma
• 基金项目: supported by the National Natural Sciences Foundation for Distinguished Young Scholar of China （No. 30725040）

This study examined the association of polymorphisms in angiotensinⅡreceptor genes(AT1R and AT2R) with the risk for aldosterone-producing adenoma(APA) in a Chinese Han population.Four polymorphisms including rs5182(573T/C) in exon 4,rs5186(1166A/C) in 3’-