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本实验旨在探讨不同量的一氧化氮对３０％酒精致大鼠胃粘膜损伤的作用和一氧化氮对肥大细胞的可能调节作用。结果揭示内源性一氧化氮对胃粘膜有保护作用，而较大剂量的外源性一氧化氮可加重胃粘膜损伤，且呈剂量依赖性，一氧化氮对胃粘膜完整性的影响可能与一氧化氮的量及机体的病理生理状态有关。有关一氧化氮与肥大细胞之间的关系本实验尚不能得出结论。
The aim of this study was to investigate the effects of different concentrations of nitric oxide on gastric mucosal injury induced by 30% alcohol and the possible regulatory effect of nitric oxide on mast cells. The results revealed that endogenous nitric oxide has a protective effect on gastric mucosa, while larger doses of exogenous nitric oxide can aggravate gastric mucosal injury in a dose-dependent manner. The effect of nitric oxide on gastric mucosal integrity may be related to The amount of nitric oxide and the body’s pathophysiological state. The relationship between nitric oxide and mast cells can not be concluded in this experiment.