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本文应用放免法检测３４例肝炎后肝硬变血清ＨＡ、ＣＧ等肝功能指标结合测量ＣＴ片上肝脾体积改变以探讨两者的关系。结果显示随着肝硬变患者Ｃｈｉｌｄ分级增加，肝功能损害加重，表现为ＨＡ和ＣＧ浓度逐渐上升，ＰＴ时间延长和白蛋白浓度降低。肝脏体积缩小，与ＨＡ、ＣＧ及ＰＴ时间呈负相关（分别为ｒ＝－０．８０４、－０．８９３、－０．８７４、Ｐ＜０．０１）及与白蛋白呈正相关（ｒ＝０．７２２、Ｐ＜０．００１），而脾脏体积改变与上述指标相反，即与ＨＡ、ＣＧ呈正相关，与白蛋白呈负相关，且ＣｈｉｌｄＡ、Ｂ、Ｃ三级之间差异显著（Ｐ＜０．００１）。结果表明，在检测肝功能的同时测量肝脏及脾脏体积可能有助于对肝硬变患者判断预后及指导治疗。
In this paper, radioimmunoassay detection of 34 cases of post-hepatitis cirrhosis serum HA, CG and other liver function indicators combined with CT volume measurement of liver and spleen volume changes to explore the relationship between the two. The results showed that with the grading of Child in cirrhotic patients, liver dysfunction increased, showing the gradual increase of HA and CG concentration, prolongation of PT and decrease of albumin concentration. The liver volume was reduced and negatively correlated with HA, CG and PT time (r = -0.804, -0.893, -0.874, P <0.01, respectively) and albumin .722, P <0.001). However, the change of spleen volume was opposite to the above index, which was positively correlated with HA and CG, negatively correlated with albumin, and there was significant difference between ChildA, B and C .001). The results show that the detection of liver function at the same time measuring the volume of the liver and spleen may help determine the prognosis of patients with cirrhosis and guide the treatment.