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人类心脏收缩的能量来自游离脂肪酸和氧的利用,即氧化磷酸化作用,所需能量的增加是通过调节冠状动脉血流,以增加输送给心肌的氧和提取物。当冠状动脉硬化时,就不能满足此需要。在氧供量明显受限制时,心肌可以通过无氧糖酵解产生能量及乳酸。Kones指出,此途径仅能提供部份的心肌需要量。尽管如此,实验和临床上仍有用葡萄糖以保存缺氧的心肌和改善其功能者,加上胰岛素和钾(合称为GTK液),可以促进心肌摄入葡萄糖以及防止低血钾。作者对9例患者进行了研究,7例为冠状动脉旁路
The energy of the human heart to contract is derived from the use of free fatty acids and oxygen, oxidative phosphorylation, and the increased energy required is to increase the flow of coronary blood to increase the oxygen and extract delivered to the myocardium. When coronary arteriosclerosis, you can not meet this need. When oxygen supply is significantly limited, the myocardium produces energy and lactate via anaerobic glycolysis. Kones pointed out that this approach can only provide some of the myocardial demand. Nevertheless, experimental and clinical use of glucose to preserve hypoxic myocardium and improve its function, coupled with insulin and potassium (collectively referred to as GTK fluid), can promote myocardial glucose intake and prevent hypokalemia. The authors conducted a study of 9 patients, 7 patients with coronary artery bypass