Assessment of Human DNA Repair （NER） Capacity With DNA Repair Rate （DRR） by Comet Assay

• 作 者: WEIZHENG JI-LIANGHE LI-PENJIN
• 机 构: InstituteofOccupationalandEnvironmentalHealth,InstiuteofOccupationalandEnvironmentalHealth
• 出 处: 生物医学与环境科学：英文版
• 发表日期: 2005年2期
• 关键词: 人类 DNA修复因子 修复速度 修复能力 NER DRR 碱性彗星实验 基因损伤 DNA repair capacity Comet assay UVC
• 基金项目: This work was supported by International Cooperation Foundation of Science-Technique Bureau of Zhejiang Province

Objective Alkaline comet assay was used to evaluate DNA repair (nucleotide excision repair, NER) capacity of human fresh lymphocytes from 12 young healthy non-smokers (6 males and 6 females). Methods Lymphocytes were exposed to UV-C (254 nm) at the dose r