论文部分内容阅读
目的了解河北省健康人群脑膜炎奈瑟菌(Nm)携带情况,为流行性脑脊髓膜炎(流脑)防治提供科学依据。方法 2006~2013年在全省11个设区市,以按年龄分层整群随机抽样方式采集健康人群咽拭子,分离培养Nm。结合流行病学调查资料对菌株检出情况进行分析。结果 8年共监测28 447人,分离到293株Nm,总带菌率1.03%;石家庄和邢台为Nm“高高”聚集区;15~24岁年龄组带菌率较高;Nm中不可分群者占45.05%,B群占14.33%,C群占12.63%,W135群占12.29%。结论建议继续加强健康人群Nm携带情况的监测,结合人群、地区分布特点及菌群变迁趋势,制定科学合理有针对性的流脑防控措施。
Objective To understand the status of Neisseria meningitides (Nm) carriers in healthy population in Hebei Province and provide a scientific basis for the prevention and treatment of epidemic cerebrospinal meningitis. Methods From 2006 to 2013, throat swabs were collected from 11 th districts and cities in the whole province to collect throat swabs from healthy population by stratified random sampling according to age. Nm was isolated and cultured. Combined with epidemiological survey data to detect the strains were analyzed. Results A total of 28 447 individuals were detected in the past 8 years and 293 Nm strains were isolated with a total carrier rate of 1.03%. Shijiazhuang and Xingtai were Nm “high ” aggregates, while those in the 15-24 age group had higher rates of infection. Nm was inseparable 45.05%, B group 14.33%, C group 12.63% and W135 group 12.29%. Conclusion It is recommended to strengthen the monitoring of Nm carrying status in healthy population. Combining population, regional distribution characteristics and trend of microbial population changes, we should develop scientific and rational targeted prevention and control measures for.