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采用动物实验及人体试食实验,对野生藜蒿提取物降低血压作用进行研究。结果发现,给予野生藜蒿提取物后的第四周,高剂量组动物血压明显下降,与对照组比较差异有显著性(P<0.05),停止给予受试物10d后血压恢复人体试食组血压平均下降15.64±11.97/10.60±8.29mmHg,收缩压下降10.12%,舒张压下降10.54%;其中有效30例,总有效率60.00%;对照组血压平均下降4.60±10.96/4.82±8.75mmHg,收缩压下降3.04%,舒张压下降5.02%其中有效16例,总有效率32.00%。两组相比差异明显(P<0.05),说明藜蒿提取物对高血压病具有明显的降低血压的作用,服用前后其尿常规及生化指标无异常。
Animal experiments and human diet experiments were conducted to study the effect of extract of Artemisia argyi on blood pressure. The results showed that the blood pressure of high dose group was significantly decreased (P <0.05) in the fourth week after the extract of Artemisia selengensis was given, and the blood pressure was restored to the test group after 10 days The average decrease of 15.64 ± 11.97 / 10.60 ± 8.29mmHg, systolic blood pressure decreased by 10.12%, diastolic blood pressure decreased by 10.54%; effective in 30 cases, total effective rate of 60.00%; control group, the average blood pressure decreased 4.60 ± 10.96 / 4.82 ± 8.75mmHg, systolic blood pressure Decreased 3.04%, diastolic blood pressure decreased 5.02% of which 16 cases were effective, the total effective rate 32.00%. There was significant difference between the two groups (P <0.05), which indicated that Artemisia selengensis extract had obvious hypotensive effect on essential hypertension. Before and after administration, the urine routine and biochemical indexes were normal.