论文部分内容阅读
本文对354名沥青作业工人进行了调查。结果表明:沥青可引起呼吸道及皮肤病变,神经衰弱综合征和食欲下降;GSHPX活性、LDH_3含量、淋巴细胞相对数和绝对数,E总、E活百分比及ANAE绝对数均较对照组明显下降,LPO、SA测定值,染色体畸变、裂隙、异常人数的检出率及微核率均明显高于对照组。提示沥青能使作业者细胞免疫功能下降,生物膜及DNA损伤,生物膜损伤可能是沥青致癌的途径之一。
In this paper, 354 asphalt workers were investigated. The results showed that: Asphalt can cause respiratory tract and skin lesions, neurasthenic syndrome and loss of appetite; GSHPX activity, LDH_3 content, lymphocyte relative number and absolute number, E total, E live percentage and absolute number of ANAE were significantly decreased compared with the control group, LPO, SA measured values, chromosome aberrations, fissures, the number of abnormal detection rate and micronucleus rate were significantly higher than the control group. Tip asphalt can make the operator decreased cellular immunity, biofilm and DNA damage, biofilm damage may be one of the ways of carcinogenic asphalt.