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目的 分析苏州地区静脉注射用免疫球蛋白(IVIG)无反应型川崎病(KD)危险因素并建立其预测评分体系.方法 回顾性分析苏州地区723例KD患儿临床资料.多因素回归分析KD患儿IVIG无反应型的危险因素.通过对危险因素赋值,建立苏州地区IVIG无反应型KD的预测评分体系.结果 年龄＜6个月、手足硬肿、中性粒细胞百分比≥80％及血清白蛋白＜35 g/L是IVIG无反应型KD独立危险因素(P＜0.05).年龄＜6个月和血清白蛋白＜35 g/L均赋予2分,手足硬肿和中性粒细胞百分比≥80％均赋予1分.以总分3分为截点值,其预测IVIG无反应型KD灵敏度为72.1％,特异度为75.3％.结论 建立了苏州地区IVIG无反应型KD的预测评分体系.临床多关注IVIG无反应型危险因素可提高对KD患儿IVIG抵抗的预测准确度.“,”Objective To analyze the risk factors of intravenous irnmunoglobulin(IVIG) in children with non-responsive Kawasaki disease(KD) in Suzhou area and establish its predictive scoring system.Methods The data of 723 children with non-responsive KD in Suzhou area were retrospectively analyzed.The risk factors of IVIG non-responsive KD were analyzed,based on which the predictive scoring system of IVIG non-responsive KD was established.Results The age less than 6 months,extremity edema,neutrophils percentage≥80％ and serum albumin＜35 g/L were the independent risk factors for IVIG non-responsive KD(P＜0.05).The age less than 6 months was scored as 2 points,serum albumin＜35 g/L as 2 points,extremity edema as one point,and neutrophils percentage≥80％ as one point.Taking 3 points as the cut-off value,the sensitivity and specificity in predicting IVIG non-reactive KD were 72.1 ％ and 75.3 ％,respectively.Conclusion Predictive scoring system of IVIG non-responsive KD in Suzhou area is established.An attention should be paid to the children with multiple IVIG non-responsive risk factors to improve the predictive accuracy of IVIG resistance in children with KD.