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缺铁性贫血是临床上常见疾病,除病因冶疗外,均需补充铁剂。但口服铁剂时若不注意配伍,就会干扰铁剂的吸收和利用,不仅达不到治疗目的,而且会增加药物的毒副反应。以下是不宜与口服铁剂配伍的常见药物: 1、抑制胃酸分泌的药物:组织胺H2—受体拮抗剂如甲氰咪胍、雷尼替丁、抗胆硷药,均能降低胃内酸度,不利于铁的吸收,故两者不宜伍用。 2、抗酸剂:碳酸氢钠、氢氧化铝等与铁剂并用,可产生难溶的复
Iron deficiency anemia is a common clinical disease, except for the cause of treatment, are required to add iron. However, if oral iron does not pay attention to compatibility, it will interfere with the absorption and utilization of iron, not only failed to achieve the purpose of treatment, but also increase the toxic side effects of drugs. The following are common drugs should not be compatible with oral iron: 1, inhibition of gastric acid secretion of drugs: histamine H2-receptor antagonists such as cimetidine, ranitidine, anticholinergic drugs, can reduce gastric acidity , Is not conducive to the absorption of iron, so both are not suitable for use. 2, antacids: sodium bicarbonate, aluminum hydroxide and iron and used in combination, can produce insoluble complex