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目的:探讨干扰素结合炎琥宁治疗小儿手足口病的临床疗效。方法:选取2013年10月-2014年11月重庆市涪陵区妇幼保健院收治的小儿手足口病患者80例,随机分成两组,每组40例,观察组采用干扰素结合炎琥宁治疗,对照组采用利巴韦林治疗,观察两组治疗效果。结果:对两组患儿进行治疗之后,观察组患儿在用药之后的退热时间、手足口部位的疱疹实际消退时间以及平均住院时间都明显短于对照组,观察组患儿的治疗总有效率为95.0%高于对照组的82.5%,差异具有统计学意义(P<0.05)。结论:对小儿手足口病患者采取干扰素结合炎琥宁的方法进行治疗,能够有效缩短患儿用药之后手足口部位的疱疹实际消退时间、实际退热时间以及平均住院时间,提高治疗总有效率。
Objective: To investigate the clinical efficacy of interferon combined with midazolam in the treatment of hand-foot-mouth disease in children. Methods: Eighty children with HFMD in Fuling District, Fuling District from October 2013 to November 2014 were randomly divided into two groups (n = 40 in each group). The observation group was treated with interferon combined with midazolam, The control group was treated with ribavirin, the treatment effect was observed in both groups. Results: After the treatment of two groups of children, the observation group patients after treatment of antipyretic time, the actual foot and mouth parts of the herpes real regression time and the average length of stay were significantly shorter than the control group, the treatment group had a total of treatment The efficiency was 95.0% higher than 82.5% of the control group, the difference was statistically significant (P <0.05). Conclusions: The treatment of HFMD in children with HFMD can effectively shorten the actual subsided time of herpes, the actual time of antipyretic fever and the average length of stay in the foot, foot and mouth of children, and improve the total effective rate of treatment .