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目的直肠癌患者行各种术式手术时,为预防局部复发或转移,甚则治疗手术不能切除的肿瘤,可加行经髂内动脉化疗泵的操作,以便术后进行局部区域性化疗。本文旨在探讨经单侧髂内动脉植入化疗药泵在中晚期直肠癌患者手术中具体操作方法及关键点的总结。方法总结25例区域性动脉化疗药泵植入术的操作方式、关键点、手术时间、出血量、术后常见症状和并发症等。结果在25例直肠癌患者行各种术式的手术时加行单侧髂内动脉植入化疗药泵植入术,平均增加手术时间20分钟,增加出血量10mL,术后胃肠恢复时间及拆线时间无明显延长,切口感染率无显著改变。结论区域性动脉化疗药泵在直肠癌术中应用是安全可行的,增加化疗浓度,减少化疗全身毒副作用,但相对局部反应明显。
Objective Rectal cancer patients undergoing various surgical procedures, in order to prevent local recurrence or metastasis, and even the treatment of unresectable tumors can be operated through the internal iliac artery chemotherapy pump in order to postoperative regional chemotherapy. This article aims to explore the single internal iliac artery chemotherapy drug pump in the operation of patients with advanced rectal cancer in the specific operation methods and key points. Methods The operation, key points, operation time, amount of bleeding, common postoperative symptoms and complications of 25 cases of regional arterial chemoembolization were summarized. Results In 25 cases of rectal cancer patients underwent various surgical procedures plus unilateral internal iliac artery implantation chemotherapy drug pump implantation, an average increase of 20 minutes of surgery, an increase of bleeding 10mL, postoperative gastrointestinal recovery time and No significant extension of stitching time, no significant change in incision infection rate. Conclusion The application of regional arterial chemotherapeutic drug pump in rectal cancer surgery is safe and feasible, increasing the concentration of chemotherapy and reducing systemic side effects of chemotherapy, but the relative local reaction is obvious.