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目的:分析中药五味汤联合吉西他滨顺铂在肺癌术后辅助化疗疗效。方法:取本院2005年7月—2010年7月间收治的非小细胞癌术后行辅助化疗的患者114例,根据治疗方法不同随机分为观察组58例与对照组患者56例。观察组患者使用GP方案+中药五味汤,对照组患者使用单纯GP方案,比较两组患者的化疗疗效、生存质量、化疗不良反应等差异。结果:两组患者接受治疗后的1年复发率及3年生存率无明显差异(χ2=0.863,P>0.05;χ2=0.795,P>0.05);观察组患者接受治疗后的生活质量(81.84±8.34)明显优于对照组患者(P<0.05);观察组患者接受治疗后的化疗不良反应(13.79%)明显少于对照组患者(P<0.05)。结论:中药五味汤联合吉西他滨顺铂可以有效提高肺癌术后辅助化疗患者的生活治疗,减少不良反应。
Objective: To analyze the curative effect of adjuvant chemotherapy of Chinese medicine Wuweitang combined with gemcitabine on postoperative lung cancer. Methods: A total of 114 patients undergoing adjuvant chemotherapy for non-small cell lung cancer who were admitted to our hospital from July 2005 to July 2010 were randomly divided into observation group (58 cases) and control group (56 cases) according to different treatment methods. Patients in the observation group were treated with the GP regimen + Chinese herbal medicine Wuwei Tang and the control group with the simple GP regimen. The differences of chemotherapy efficacy, quality of life and adverse reactions of chemotherapy between the two groups were compared. Results: There was no significant difference in the 1-year recurrence rate and 3-year survival rate between the two groups after treatment (χ2 = 0.863, P> 0.05; χ2 = 0.795, P> 0.05) ± 8.34) was significantly better than that of the control group (P <0.05). Adverse reaction (13.79%) in the observation group was significantly less than that in the control group (P <0.05). Conclusion: Chinese medicine Wuwei Decoction combined with gemcitabine cisplatin can effectively improve the life of postoperative adjuvant chemotherapy in patients with lung cancer and reduce adverse reactions.