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目的观察胸腺肽对反复呼吸道感染（ＲＲＴＩ）病儿红细胞免疫黏附功能的影响。②方法采用酵母菌花环法检测胸腺肽治疗前后ＲＲＴＩ病儿红细胞免疫Ｃ３ｂ受体花环率（Ｅ－Ｃ３ｂＲＲ）和红细胞免疫复合物花环率（Ｅ－ＩＣＲ）的变化。③结果ＲＲＴＩ病儿感染急性期和间歇期Ｅ－Ｃ３ｂＲＲ皆明显低于对照组（Ｆ＝１５．５４，ｑ＝７．８７，４．３７，Ｐ＜０．０１），而Ｅ－ＩＣＲ组间比较差异无显著性（Ｆ＝２．１１，Ｐ＞０．０５）。胸腺肽治疗后ＲＲＴＩ病儿Ｅ－Ｃ３ｂＲＲ显著增高，与治疗前比较差异有极显著性（ｔ＝６．５８，Ｐ＜０．０５），而Ｅ－ＩＣＲ治疗前后差异无显著性。④结论ＲＲＴＩ病儿存在原发性红细胞免疫功能低下。胸腺肽对ＲＲＴＩ病儿红细胞免疫黏附功能有明显增强作用。
Objective To observe the effect of thymosin on erythrocyte immune function in children with recurrent respiratory tract infection (RRTI). Methods The changes of E-C3bRR and E-ICR of erythrocyte immune complex before and after thymosin treatment were detected by yeast wreath method. Results The E-C3bRR levels in acute and intermittent RRTI infected children were significantly lower than those in control group (F = 15.54, q = 7.87, 4.37, P <0.01) There was no significant difference (F = 2.11, P> 0.05). The E-C3bRR of RRTI children after thymosin treatment was significantly higher than that before treatment (t = 6.58, P <0.05), but there was no significant difference between before and after E-ICR treatment. ④ Conclusion RRTI sick children have primary erythrocyte immune dysfunction. Thymosin on RRTI sick children erythrocyte immune adhesion function was significantly enhanced.