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近几年,特异性活质分子受体显像肿瘤已成为人们关注的焦点。血管活性(物质)肠肽(VIP)对特异性受体有高的亲合力,表现为在大多数恶性肿瘤有高的密度。此研究检查了它的药物动力学并测定了99mTc-TP3654显像人肿瘤的可行性。方法 用99mTc标记修改过的VIP(TP3654)。3例健康志愿者?
In recent years, specific active molecular imaging of tumor receptors has become the focus of attention. Vasoactive (substance) intestinal peptide (VIP) has a high affinity for specific receptors, manifested as high density in most malignancies. This study examined its pharmacokinetics and determined the feasibility of 99mTc-TP3654 imaging of human tumors. Methods The modified VIP (TP3654) was labeled with 99mTc. 3 healthy volunteers?