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作者探讨了血管内皮生长因子 (ＶＥＧＦ)和内皮素 (ＥＴ) -1在低氧性肺动脉高压 (ＨＰＨ)及其肺血管重建中的作用 ,并观察钾通道开放剂 (Ｐｉｎａｃｉｄｉｌ)对ＨＰＨ的防治作用及对ＶＥＧＦ和ＥＴ -1的影响。把 4 6只Ｗｉｓｔｅｒ大鼠 ,随机分为 3组 ,对照组 1 5只 ,低氧组 1
The authors investigated the role of vascular endothelial growth factor (VEGF) and endothelin (ET) -1 in hypoxic pulmonary hypertension (HPH) and pulmonary vascular remodeling and the preventive and therapeutic effects of potassium channel opener (Pinacidil) on HPH And the effects on VEGF and ET-1. Forty-six Wister rats were randomly divided into three groups: control group (15) and hypoxia group (1)