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目的：心房纤颤( Atrial fibrillation, AF)是急性脑梗死( Acute ischemic stroke, AIS)的一种重要危险因素。我们比较AF患者与非AF患者AIS的临床与影像学特点。方法：本研究把入选的196名AIS患者根据是否存在AF分为AF组与非AF组,分别比较两组患者的基本信息、危险因素、临床特点和影像学特点。结果：与非AF组相比, AF组患者年龄较大,女性患者所占比例偏高。 AF组入院时美国国立卫生院神经功能缺损( NIHSS )评分与出院时改良 Rankin 量表( mRS)评分皆高于对照组。多发性梗死灶、皮层梗死及出血转化在AF患者中更多见。结论：临床与弥散加权成像特点有助于对AF患者发生的AIS早期明确病理学机制提供线索与帮助。“,”OBJECTIVE: To compared the clinical and neuroimaging characteristics of acute ischemic stroke ( AIS) in patients with AF or without AF. METHODS: 196 subjects were enrolled in the study and divided into the AF and non-AF group. The study compared demographic characteristics, cerebrovascular risk factors, clinical and neuroradiological data of patients in two groups. RE-SULT: Patients with AF were older than those without AF. Patients with AF were associated with higher National Institutes of Health Stroke Scale scores on admission and higher modified Rankin Scale at discharge. The patients in AF group had more frequently hemor-rhagic transformation, multiple infarcts and cortical infarction than those in non-AF group. CONCLUSION: Clinical and diffusion weighted imaging features of AIS may help clinicians to easily make the diagnosis of cardiac emboligenic condition in patients with AF.